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Guardant Health was founded in 2012 by AmirAli Talasaz and Helmy Eltoukhy. Guardant Health launched its first commercial sequencing test, Guardant360, in 2014. In 2016, Guardant Health launched GuardantOMNI, a comprehensive liquid biopsy test with best-in-class accuracy. In 2018, the company launched Guardant Reimbursement Solutions, which works to make sure patients get reimbursed for their tests.