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.406 Ventures

Early-stage venture capital firm that invests in innovative Information Technology (“IT”) and services companies founded by the finest entrepreneurs.
.406 Ventures
Leadership team

Liam Donohue (Co-Founder and Managing Partner)

Maria Cirino (Co-Founder and Managing Partner)

Greg Dracon (Partner)

Graham Brooks (Partner)

Payal Agrawal Divakara (Partner)

Number of Employees
50 - 100
Headquarters
Boston, MA, United States
Established
2005
Social Media
Summary

.406 Ventures is a venture capital firm that specializes in investing in early-stage companies in the technology and healthcare sectors. The firm was founded in 2006 and is based in Boston, Massachusetts. 406 Ventures focuses on investing in companies that are developing innovative technologies and business models that have the potential to transform industries and create significant value.

The firm's investment criteria include a focus on companies that are solving complex problems, have strong intellectual property, and are led by experienced and passionate management teams. .406 Ventures also looks for companies that are addressing large and growing markets, have clear paths to commercialization, and have the potential to generate strong returns for investors.

History

.406 Ventures is a venture capital firm that was founded in 2006 by Liam Donohue, Maria Cirino, and Payson Swaffield. The firm is based in Boston, Massachusetts, and focuses on investing in early-stage companies in the technology and healthcare sectors.

Prior to founding .406 Ventures, Liam Donohue was a general partner at .406 Ventures, a venture capital firm that was later acquired by Bessemer Venture Partners. Maria Cirino was the founder and CEO of Guardent, a provider of managed security services that was acquired by VeriSign. Payson Swaffield was a managing director at Cambridge Associates, a global investment firm.

Since its founding, .406 Ventures has raised several funds and has invested in over 50 companies. The firm's first fund, raised in 2007, had $170 million in commitments, and its second fund, raised in 2013, had $207 million in commitments. In 2019, the firm closed its third fund with $294 million in commitments.

406 Ventures invests in companies that have a unique technology platform and a strong market potential. The firm's areas of focus include enterprise software, data and analytics, cybersecurity, digital health, and medical devices. The firm takes a partnership approach to working with entrepreneurs, providing not just capital but also strategic guidance and operational support.

Investment criteria

.406 Ventures invests in companies that are typically past the seed stage and have some traction in the market, such as early customer adoption or revenue. The firm's typical initial investment ranges from $2 million to $10 million, with the potential for follow-on investments as the company grows.

The firm's areas of focus include enterprise software, data and analytics, cybersecurity, digital health, and medical devices. Within these sectors, .406 Ventures looks for companies that have a differentiated product or service offering and a strong management team.

In addition to financial support, .406 Ventures provides operational and strategic guidance to its portfolio companies. The firm's experienced team works closely with entrepreneurs to help them build and scale their businesses. This includes support in areas such as sales and marketing, product development, talent acquisition, and fundraising.

Values
  • Partnership: .406 Ventures believes that successful investments are built on strong partnerships between investors and entrepreneurs. The firm works closely with its portfolio companies to provide strategic guidance and operational support, and to help them achieve their goals.
  • Innovation: The firm is dedicated to supporting companies that are developing innovative solutions to complex problems. It believes that breakthrough technologies and new business models have the potential to transform industries and create significant value.
  • Integrity: .406 Ventures is committed to upholding the highest ethical standards in all of its dealings. The firm believes that honesty, transparency, and accountability are essential to building trust with entrepreneurs and investors.
  • Collaboration: The firm values collaboration and believes that working together with entrepreneurs, investors, and other stakeholders is key to driving innovation and creating value.
  • Diversity and inclusion: .406 Ventures is committed to fostering a diverse and inclusive community of entrepreneurs, investors, and partners. The firm believes that diversity of thought and perspective is essential to driving innovation and creating value.
  • Community: The firm is committed to giving back to the community and supporting initiatives that promote social and environmental responsibility. It believes that businesses have a responsibility to create a positive impact and contribute to the greater good.
Mission

The firm believes that breakthrough technologies and new business models have the power to disrupt traditional industries and create new opportunities. It is dedicated to supporting companies that are developing unique solutions to complex problems, and that have the potential to achieve significant growth and impact.

406 Ventures is committed to providing more than just financial support to its portfolio companies. The firm's experienced team works closely with entrepreneurs to provide strategic guidance and operational support, helping them to navigate the challenges of scaling their businesses.

Portfolio

406 Ventures has a diverse portfolio of companies in the technology and healthcare sectors. Here are some examples of companies in the firm's portfolio:

  • Algorand: Algorand is a blockchain platform that enables developers to build decentralized applications. The platform is designed to be scalable, secure, and decentralized, and it has been used for applications such as asset tokenization and supply chain management.
  • Attentive: Attentive is a personalized mobile messaging platform that enables businesses to engage with their customers through text messaging. The platform is used by e-commerce, retail, and other businesses to increase customer engagement and sales.
  • Biofourmis: Biofourmis is a digital therapeutics company that uses AI-powered analytics to provide personalized care for patients with chronic conditions. The company's platform is used by healthcare providers to monitor patients remotely and improve outcomes.
  • Cogito: Cogito is a behavioural analytics company that uses AI-powered software to analyze customer interactions and provide real-time coaching for customer service representatives. The platform is used by businesses to improve customer satisfaction and increase sales.
  • DraftKings: DraftKings is a digital sports entertainment and gaming company that offers daily fantasy sports and online sports betting. The company is one of the largest operators in the sports betting industry and has partnerships with major sports leagues and teams.
  • PillPack: PillPack is a digital pharmacy that provides personalized medication management for patients with chronic conditions. The company was acquired by Amazon in 2018.
References
.406 Ventures
Leadership team

Liam Donohue (Co-Founder and Managing Partner)

Maria Cirino (Co-Founder and Managing Partner)

Greg Dracon (Partner)

Graham Brooks (Partner)

Payal Agrawal Divakara (Partner)

Number of Employees
50 - 100
Headquarters
Boston, MA, United States
Established
2005
Social Media