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Akebia Therapeutics was founded in 2007 by Marc Otte, an experienced pharmaceutical executive, and Doug Harker, a noted biomedical entrepreneur and angel investor. The company was initially focused on the discovery and development of novel treatments for anemia. Over the course of the following four years, Akebia secured financing from strategic partners, acquired novel assets and built a world-class development and commercialization team. In 2014, Akebia secured a new round of financing, bringing its total investment to date to more than $100 million.