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Last Updated: 2026
Apellis Pharmaceuticals image

Apellis Pharmaceuticals

Rank#3174
Market Cap5.25B
CountryUnited States
Summary
History
Mission
Vision
References
Summaryarrow
Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases. The company's lead product candidate is pegcetacoplan that is in Phase III clinical trials for the treatment of geographic atrophy (GA) in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria (PNH) diseases. It also develops EMPAVELI (systemic pegcetacoplan) for the treatment of cold agglutinin disease (CAD), and hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-TMA) in hematology; C3 glomerulopathy (C3G), and immune complex membranoproliferative glomerulonephritis (IC-MPGN) in nephrology; and amyotrophic lateral sclerosis (ALS) in neurology. In addition, the company develops APL-2006, a bispecific C3 and VEGF inhibitor for treating complement-mediated disorders; APL-1030, a C3 inhibitor for the treatment of multiple neurodegenerative diseases; and the combination of EMPAVELI and a small interfering RNA, or siRNA for reducing the production of C3 proteins by the liver. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) to co-develop pegcetacoplan; and a research collaboration with Beam Therapeutics Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is based in Waltham, Massachusetts.
Historyarrow

Apellis Pharmaceuticals, Inc. (NASDAQ: APLS) is a global biopharmaceutical company focused on the development of innovative therapies to address an unmet need in places where the greatest opportunity for meaningful outcomes for patients exists. The Company’s differentiated, Complement-Based platform has the potential to treat a variety of diseases with a wide range of therapeutic indications, including ophthalmic, rare diseases, and other immunologic and chronic conditions. In June 2015, Apellis Pharmaceuticals was founded by Dr. Ciro de Quadros and Dr. Cedric Francois, who have extensive and highly successful histories in drug development and commercialization. Both founders were also instrumental in driving the science and development behind a number of blockbuster drugs.

Missionarrow
Apellis Pharmaceuticals is committed to providing novel and effective therapies to dramatically improve the health and quality of life of patients with devastating diseases.
Visionarrow
Apellis Pharmaceuticals’s vision is to become the global leader for innovation in the development of life-changing therapies for serious diseases.
Referencesarrow

https://in.investing.com/equities/apellis-pharma

https://finance.yahoo.com/quote/APLS/profile?p=APLS

https://www.crunchbase.com/organization/apellis-pharmaceuticals

https://sec.report/CIK/0001492422

https://companiesmarketcap.com/

https://www.apellis.com

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Leadership team
D
Dr. Cedric Francois M.D., Ph.D. (Co-Founder, Pres, CEO & Director)
D
Dr. Pascal Deschatelets Ph.D. (Co-Founder & Chief Scientific Officer)
D
Dr. Federico Grossi M.D., Ph.D. (Co-Founder & Chief Medical Officer)
Products / Services
Biotechnology, Health Care, Pharmaceutical, Therapeutics
Number of Employees
100 - 500
Address
Waltham, Massachusetts, United States
Established
2008-01-01
Company Registration
SEC CIK number: 0001492422
Revenue
100M - 500M
Traded as
APLS
Website
https://www.apellis.com
Social Media
linkedinx
Last Updated: 2026
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