Summary
Celyad Oncology SA, a clinical-stage biopharmaceutical company, focuses on the discovery and development of chimeric antigen receptor T (CAR-T) cell therapies for the treatment of cancer. Its lead product candidates include CYAD-101, an allogeneic CAR-T candidate that is in Phase 1b clinical trial for the treatment of metastatic colorectal cancer; CYAD-211, a short hairpin RNA (shRNA)-based allogeneic CAR-T candidate, which is in Phase 1 clinical trial to treat relapsed / refractory multiple myeloma; and CYAD-02, an autologous CAR-T candidate that is in Phase 1 clinical trial for the treatment of relapsed or refractory acute myeloid leukemia and myelodysplastic syndromes. The company's preclinical candidate includes CYAD-203, a non-gene edited allogeneic CAR-T candidate to co-express the cytokine interleukin-18 with natural killer group 2D ligands (NKG2D) for the treatment of solid tumors. It has licensing agreement with Novartis International AG regarding the United States patents related to allogeneic CAR-T cells; and research and development collaboration, and license agreements with Horizon Discovery Group plc for the use of its shRNA technology to generate second non-gene-edited allogeneic platform. The company was formerly known as Celyad SA and changed its name to Celyad Oncology SA in June 2020. Celyad Oncology SA was founded in 2004 and is headquartered in Mont-Saint-Guibert, Belgium.
History
Celyad was founded in 2007 and has its co-headquarters in Mont-Saint-Guibert and New York. The company provides innovative therapeutics to patients suffering from severe life-threatening diseases. It harnesses the power of cardiomyocytes-derived stem cells to develop treatments for heart failure, cancer and autoimmune diseases.
Mission
Our mission is to enable access to CAR-T cell-based treatments to patients in need by developing best-in-class treatments and advancing patient care.
Vision
Our vision is to be the leading provider of advanced CAR-T cell therapies and to continue to set the standard for care that is safe, effective and accessible for all patients in need.
Key Team
Mr. Philippe Nobels (Chief HR Officer & VP of HR)
Dr. Charles Q. Morris M.D., MBChB, MRCP (UK), Ph.D. (Chief Medical Officer)
Ms. An Phan (Head of Legal)
Mr. Hannes Iserentant (Head of Intellectual Property)
Dr. Frédéric Lehmann (VP of Clinical Devel. & Medical Affairs)
Recognition and Awards
Celyad has been recognized with numerous awards, including being a Finalist for the 2020 Prix Galien USA, being named a Gairdner Laureate in 2017, and winning the Prix Mont-Saint-Guibert in 2010.
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