Summary
PureTech Health plc, a clinical-stage biotherapeutics company, discovers, develops, and commercializes medicines for inflammatory, fibrotic and immunological, intractable cancers, lymphatic and gastrointestinal, neurological and neuropsychological, and other diseases in the United States. The company offers KarXT targeting muscarinic acetylcholine receptors to treat schizophrenia and psychosis in Alzheimer's disease; a regenerative biology platform for androgenetic alopecia, epithelial ageing, and other medical conditions; an immunomodulation platform to treat chronic and acute inflammatory disorders; oral therapies based on defined consortia of bacteria is isolated from the human microbiome; and therapies to treat cognitive dysfunction associated with depression, multiple sclerosis, post COVID and ICU, and cancer related conditions. It also provides hematopoietic stem cell based therapies for patients with blood cancer; a voice-based technology platform to detect voice changes linked to health conditions; and a technology platform for the oral delivery of biologics, vaccines, and other drugs. In addition, the company is developing LYT-100 to treat lymphedema, and other lymphatic flow disorders; LYT-200, a IgG4 monoclonal antibody to target galectin-9; LYT-210 to treat solid tumors; Glyph, a synthetic lymphatic targeting chemistry platform; Orasome technology to enable the oral administration of macromolecule therapeutic payloads; meningeal lymphatics platform to treat Alzheimer's and Parkinson's diseases; and Alivio technology platform for inflammation-targeted disease immunomodulation. PureTech Health plc has collaboration and license agreements with Boehringer Ingelheim International GMBH; Eli Lilly and Company; Imbrium Therapeutics L.P.; and Shionogi & Co., Ltd. The company was incorporated in 2015 and is headquartered in Boston, Massachusetts.
History
The company was founded by Daphne Zohar, an American entrepreneur, in 2005. It was the subject of an initial public offering on the London Stock Exchange in June 2015.
Mission
PureTech Health is committed to discovering, developing, and commercializing novel medicines to tackle serious unmet medical needs and improve the lives of patients
Vision
PureTech Health is devoted to transform healthcare through the integration of advanced science, novel technologies and innovative treatments.
Key Team
Dr. Joseph B. Bolen (Chief Scientific Officer)
Dr. Bennett M. Shapiro M.D. (Co-Founder & Board Advisor)
Ms. Allison Mead Talbot (Head of Communications & Investor Relations)
Dr. David R. Elmaleh Ph.D. (Co-Founder & Sr. Advisor)
Mr. Spencer Ball (Sr. VP of HR)
Dr. Eric Elenko Ph.D. (Chief Innovation & Strategy Officer)
Ms. Aleksandra Filipovic M.D., Ph.D. (Head of Oncology)
Recognition and Awards
The company has been recognized as one of Fortune's 100 Fastest-Growing Companies in 2017, and was featured in the 2016 Fierce Biotech Innovation Awards.
References
United States 